GMP Cleaning Services

If your business manufactures food, beverages, or pharmaceutical products, dietary supplements, cosmetics, or medical devices that require FDA approval, you understand the rigors of Current Good Manufacturing Practices (CGMP). It is equally likely that your manufacturing processes exceed CGMP requirements, ensuring that your products consistently meet their quality standards and specifications.

As the leading provider of GMP cleaning services in the Baltimore-Washington, DC region, we take your CGMP practices as seriously as you do. That means we follow your GMP cleaning requirements meticulously. And while we may offer recommendations based on our years of cleaning experience, you know your GMP needs best. Therefore, your cleaning process becomes our process, and we will not deviate from your documented GMP cleaning procedures.

We provide GMP cleaning services in Central and Northern Maryland, as well as Northern Virginia and parts of Washington, DC.

The GMP Cleaning Process

GMP Cleaning & Sanitation

Cleaning and sanitation are both needed to reduce the potential of contamination that could negatively impact the purity of the end product. Cleaning is the physical removal of visible and microscopic contamination by dirt, extraneous material, and product residues. GMP cleaning is usually followed by visual inspection, and then laboratory testing to verify that the cleaning process is effective. Sanitation is the reduction of microbiological contamination. It is usually achieved by the use of chemicals. It may be necessary to remove chemical residues with additional cleaning. This can be mitigated by adhering to the correct standards of concentration, pH, and temperature. Learn more about Cleaning and Sanitizing.
GMP Facility Cleaning

If a GMP manufacturing facility produces multiple products simultaneously, the primary means of preventing cross-contamination between cleanrooms is air pressure. Negative air pressure prevents particulate matter from escaping a room, and positive air pressure prevents particulate matter from entering it. If these pressures are lost, then there is a risk of cross-contamination. To prevent cross-contamination during the cleaning process, clothing (i.e., clean suits) must be changed when moving between manufacturing areas. Additionally, only the cleaning agents and tools specified for that area may be used.
GMP Equipment Cleaning

The cleaning of equipment that comes into contact with products during their manufacture is of special attention during GMP cleaning. Equipment that is not cleaned according to documented procedures are likely to contaminate future product batches. Is is also possible that clean equipment can be contaminated in storage or if not allowed to dry properly. Therefore, GMP places special emphasis on effective and validated cleaning and storage of all equipment that comes into contact with products being manufactured.
GMP Cleaning Validation

Product quality must be ensured in every step of the GMP process, and no amount of laboratory testing can take the place of prevention measures. Meticulous cleaning records verify that each piece of equipment used in the manufacturing area was performed by trained cleaning personnel using validated written procedures.